slingshot pseudotime analysis

Single-Cell Transcriptomic Comparison of Human Fetal The pseudotime analysis program Slingshot aligned cells along a 2D trajectory from the most transcriptionally similar LaTP population (LaTP-SynTII; LaTP2-SynTI; LaTP2-STGC) to each of the mature populations (Street et al., 2018; Figure 2C–E, Figure 2—source datas 2–4). シングルセルRNA-seq解析 | 株式会社ジエンブル - Genble Provides functions for inferring continuous, branching lineage structures in low-dimensional data. If TRUE (default), cells that are not assigned to a lineage will have a pseudotime value of NA.Otherwise, their arclength along each curve will be returned. Slingshot Critical downstream analysis steps for single-cell RNA sequencing … We have introduced a novel method, Slingshot, for lineage and pseudotime inference in single-cell genomics data. Because Slingshot breaks the inference problem into two steps, we are able to make use of appropriate methods for each task and avoid the common trade-off between stability and the flexibility to detect complex structures. analysis

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